Leopoldina is a Brazilian municipality in the state of Minas Gerais. It belongs to the Zona da Mata mesoregion and it located 322 kilomete…Leopoldina is a Brazilian municipality in the state of Minas Gerais. It belongs to the Zona da Mata mesoregion and it located 322 kilometers southeast of Belo Horizonte, the state capital. In 2022, its estimated population was 51 145 inhabitants, according to IBGE. Its territory covers an area of 943 km.