Dressed as a boxer, he then takes a victory lap with his supporters. “Pfizer is fighting for 8 cancer breakthroughs by 2030,” reads text near the end of the spot, which then directs viewers to PfizerForAll.com.

Last year marked the first time in Pfizer’s 175-year history that the drugmaker shelled out the requisite millions for

Thanks in part to LL Cool J ‘s “Mama Said Knock You Out,” Pfizer’s new Super Bowl commercial will leave viewers feeling hyped about the medical company’s ongoing cancer research — but because of the inspiring message at its center, it’ll also likely leave you in tears.

Pfizer is doubling down on its fight against cancer with a 60-second ad set to air during the first quarter of the game.

Picking up from where last year's Big Game ad debut left off, Pfizer wants to bring a note of resilience and motivation to those fighting cancer in its Super Bowl 59 spot. In the ad, a young boy gets out of his hospital bed,