The American strikes come amid an intensifying, parallel drive by U.S. ally Israel, which has launched its own series of airstrikes on Houthi targets in response to recent missile and drone attacks on Israel that, while mostly intercepted, have struck some civilian sites and have sent millions seeking regular refuge in bomb shelters.

A missile fired by Yemen’s Houthi rebels targeted central Israel early Tuesday, sounding sirens and causing people to flee into bomb shelters. The Israeli military said “several attempts were made to intercept a missile that was launched from Yemen.

Members of a police bomb disposal unit work to evacuate parts of a ballistic missile fired from Yemen overnight, which landed on the roof of a house in Moshav Mevo Beitar, on the outskirts of Jerusalem.