Cardinals quarterback Kyler Murray made big plays with his arm and his legs, running back James Conner fought for some tough yardage, and on the 49ers' last offensive play, Brock Purdy got drilled ...

When the Cardinals last played the 49ers, Conner was a problem rushing for 86 yards, averaging 4.5 yards per carry. With gone, the 49ers will have a much easier matchup defending.

The 49ers are headed back to the playoffs after blowing out the Cardinals for the second time this season, capping their 10-game win streak with a 38-13 rout.

Check out our 49ers vs. Cardinals how to watch guide to learn when they play and what free live streams are available ahead ... 49ers: Beat the Patriots 30-13 during ... shirts and more gear: ...

The San Francisco 49ers have officially clinched the NFC West division title after beating down the Arizona Cardinals. It wasn't a close game at all despite how the final score is presented.

The San Francisco 49ers defeated the Arizona Cardinals 38-10 in Mexico City on Monday. Stay tuned into this live blog from The Athletic for breaking news, updates, inactives, scores and more from ...

The Cardinals have gone 2-2 since the return of Kyler Murray in Week 10. Murray is still knocking off some rust; he has a 60.8 completion percentage and has thrown three touchdowns in his four games.

BetMGM NFL odds: 49ers by 7 1/2. Against the spread: Cardinals 2-2; 49ers 2-2. Series record: 49ers lead 36-29. Last meeting: 49ers beat Patriots 45-29 in Glendale, Ariz., on Dec. 17, 2023. Last ...

Kyler Murray threw for 242 yards and four touchdowns, two to Greg Dortch, and the Arizona Cardinals beat the injury-depleted San Francisco 49ers 47-24. Latest U.S.

The San Francisco 49ers will wrap up the 2022 regular season by hosting the Arizona Cardinals on Sunday. Not only will they have the opportunity to finish the schedule with a 10-game winning ...

When the Cardinals last played the 49ers, Conner was a problem rushing for 86 yards, averaging 4.5 yards per carry. With gone, the 49ers will have a much easier matchup defending.

The Cardinals dominated the second half today against the 49ers, pulling off a road upset in a game that may prove to have major ramifications in the NFC West race. Cardinals quarterback Kyler ...