The liver is a vital organ, crucial to digestion, metabolism and the elimination of toxins. It has a unique ability, regeneration, which allows it to replace liver cells damaged by the very toxins ...

A study conducted by Prof. Thai-Yen Ling at National Taiwan University underscores the potential of small extracellular ...

Researchers discovered a mechanism after acute liver damage occurs—and it could lead to treatments for those with severe liver problems.

After acute liver damage, liver cells, called hepatocytes ... The experiments were conducted in animal models, but the ...

HHMI researchers solve a longstanding mystery about the origin of new cells in the liver. Howard Hughes Medical Institute (HHMI) scientists have identified stem cells in the liver that give rise to ...

We transiently transfected 293T and 293TGP cells (a gift from G.P. Nolan ... 30–40 random areas of the sections from 2–3 liver lobes; 2,000 nuclei from each animal). Student's t-test was ...

Researchers at the German Cancer Research Center Deutsches Krebsforschungszentrum (DKFZ) and their collaborators have cast new light on the mechanisms by which hepatic stellate cells control liver ...

Ammonia buildup damages liver cells by harming mitochondria, leading to cell death and liver injury. An existing drug, YAQ-005, can prevent this damage by halting mitochondrial harm, allowing ...

New research suggests restoring stellate cells to their healthy and protective state could simultaneously reduce liver scarring and improve liver function.

High levels of ammonia kill liver cells by damaging the mitochondria that power the cells. But this can be prevented using an existing drug due to start clinical trials, finds a new study in mice.