Bile acid metabolism disorders encompass a range of rare, yet clinically significant, genetic conditions that disrupt the normal synthesis and regulation of bile acids by the liver. These conditions, ...

Primary biliary cholangitis (PBC) is a chronic progressive autoimmune disorder characterized by small non-purulent ...

The study details the connection between SCARB2 deficiency and gastrointestinal dysfunction, revealing that the loss of SCARB2 leads to alterations in bile acid metabolism and dysbiosis in the gut ...

A study published in the journal Cell Metabolism finds that hyodeoxycholic acid alleviates non-alcoholic fatty liver disease by modulating the gut-liver axis. Study: Hyodeoxycholic acid alleviates non ...

Liver is the major organ for metabolism of sulfur amino acids (methionine, cysteine, taurine) and expresses high levels of sulfur amino acid synthesis and metabolising enzymes. Dietary intake, ...

Many of us attribute gradual weight gain in middle age and beyond to a slow metabolism, but to what extent is this assumption true?In a world flooded with health advice and ever-changing diet trends, ...

Over the years, researchers have amassed strong evidence that caloric restriction can extend lab animals’ lives. Unfortunately, extending those benefits to humans has proved difficult, in part because ...

Mice that switched from a high sugar/butter diet to a standard diet developed a strong preference for alcohol over water, in ...