Two recent studies identified gene knockouts that may make CAR T-cell therapy more effective, but the next step is applying ...

Buildup of acidic byproducts in pancreatic tumors alleviates the effects of other environmental stresses and aids the cancer.

Natural systems such as CRISPR-associated transposons (CASTs) offer a targetable, one-step way to edit genomes. However, adapting them for biomedical applications has been challenging. To address this ...

The entire rationale behind this multi-pronged screening was the discovery of checkpoints or regulators that are critically ...

In biology’s standard tale of two acids — deoxyribonucleic (DNA) and ribonucleic (RNA) — RNA is merely the messenger. Its better-known cousin DNA plays the lead role, issuing genetic instructions for ...

More than 10 million people develop tuberculosis (TB) each year, yet about 40% go undiagnosed. The main culprit is reliance on sputum-based testing, which many patients—particularly those who are ...

The obesity rate has more than doubled in the last 30 years, affecting more than one billion people worldwide. This prevalent condition is also linked to other metabolic disorders, including type 2 ...

CRISPR Therapeutics (Nasdaq: CRSP), a biopharmaceutical company focused on creating transformative gene-based medicines for ...