Renal drug excretion involves filtration, reabsorption, and secretion, crucial for drug clearance and minimizing toxicity. The study models renal clearance using pharmacokinetic parameters, validated ...

Please provide your email address to receive an email when new articles are posted on . The “strong associations” of urine-to-plasma ratios with cardiovascular mortality implies a connection between ...

Nat Clin Pract Cardiovasc Med. 2006;3(2):102-109. With the increasing prevalence of congestive heart failure in our aging population, treatment with inotropes, pressors and natriuretic peptides is no ...

Upon intravenous administration, NPs and NMs enter the vascular system and are distributed to the organs and peripheral tissues of the body. Within the vascular compartment these particles or ...

The urinary recovery of nitrofurantoin after a single 100-mg oral dose was studied in subjects with varying renal function. Almost all uremic patients excreted little or no drug in the urine during a ...

HYDROCHLOROTHIAZIDE (6-chloro-7-sulfamyl-3,4,dihydro-l,2,4, benzothiadiazine-1,1,-dioxide) is the 3,4,dihydro derivative of chlorothiazide wherein the 3,4 double bond is saturated by two hydrogen ...

Please provide your email address to receive an email when new articles are posted on . In the United States, the annual rate of growth in incident patients with end-stage kidney disease has slowed.