Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...
Cellular mechanical states modulate cytoskeleton–nucleus links and trigger the translocation of regulatory molecules to the nucleus. The remodelling of cytoskeleton–nucleus links results in distinct ...
IN his presidential address to the Royal Microscopical Society delivered on Jan. 20, Prof. R. Ruggles Gates reviewed present knowledge regarding nuclear structure, especially in relation to genetics.
Researchers from Skoltech, the University of Potsdam, and the Massachusetts Institute of Technology have discovered a ...
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Hidden cell structures reveal a common weakness in leukemia
A hidden structure inside the cell is rewriting how scientists understand leukemia. Beneath the microscope, what looked like ...
Researchers at the Kennedy Institute have provided the most comprehensive overview to date of how the distinctive segmented ...
The Kanazawa team led by Katsuya Sakai, discovered that CHD1 uses a flexible region to form tiny liquid-like droplets, called condensates, that act as hubs for controlling the activity of crucial ...
AFM, which inserts a nanoneedle probe directly into cells, scientists revealed how cancer cell nuclei stiffen or soften ...
Researchers at the Francis Crick Institute have shown that the 'pacemaker' controlling yeast cell division lies inside the nucleus rather than outside it, as previously thought. Having the pacemaker ...
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