For almost a century, our understanding of the tiny structure at the centre of the cell called the centrosome was limited to its ability to organize mitotic spindles and other microtubule arrays.
Centrosome duplication is tightly regulated to ensure that centrioles duplicate only once per cell cycle and that only one new centriole is produced per pre-existing centriole Phosphorylation events ...
A dividing cell duplicates its chromosomes and its centrosome, an organelle that helps divide the two sets of chromosomes equally to daughter cells, just once. Extra centrosome copies can lead to ...
In humans and other mammals, cardiac muscle cells stop replicating soon after birth, unlike the cardiac muscle cells in, say, zebrafish and amphibians. What do zebrafish and amphibian cardiomyocytes ...