JA Rosenfeld is an employee of Signature Genomic Laboratories, a subsidiary of PerkinElmer, Inc. The authors have no other relevant affiliations or financial involvement with any organization or ...

Human egg cells are often prone to chromosomal errors. As women age, the error rate increases sharply — and can contribute to infertility, pregnancy loss, and ...

Chronic myeloid leukemia (CML) is a rare blood cancer that develops in the bone marrow. Karyotyping is a genetic technique doctors use to diagnose CML and choose more effective treatments. Karyotyping ...

Around 1 in 500 men carry an extra X or Y chromosome, according to a large study published this week in Genetics in Medicine. But most of those affected are unaware of their status, despite it ...

Abnormalities in the structure of chromosomes within someone’s genetic makeup are called structural chromosomal abnormalities. Robertsonian translocations are very rare structural chromosomal ...

Chronic myeloid leukemia (CML) is a chronic type of leukemia. It’s also called chronic myelogenous leukemia. CML occurs when an abnormal gene allows cancer to spread in your body. Researchers have ...

Each workday, Dr. Jannine Cody walks past bulletin boards that display photos of hope. The boards line three tiled walls on the fifth floor, home to the Chromosome 18 Clinical Research Center at UT ...

Only a small minority of these men had a diagnosis of sex chromosome abnormality on their medical records or by self-report: fewer than one in four (23%) men with XXY and only one of the 143 XYY men ...