Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren't ...
The first theoretical model of condensin, a molecular machine involved in packing and unpacking chromosomes, accurately reproduces all known experiments with just two parameters. To scrunch a ...
The most accurate quantitative model yet for understanding the role of condensin during cell division is also visually stunning. A team of scientists from UT Austin have developed the most accurate ...
La Jolla Institute for Immunology Associate Professor Ferhat Ay, Ph.D., is building some of the world's smallest maps. Dr. Ay harnesses computers to transform DNA genomic sequences into 3D maps. These ...
An article by UAB professor Joan-Ramon Daban analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study ...
Different types of cell division failure shape whether duplicated cells survive, remain stable, or lead to cancer.
When bacteria cells replicate, they do so a little differently than human cells do. They don't undergo mitosis, a splitting that involves construction of spindles to carefully separate the DNA after ...
A research team led by geneticist Jeannie Lee at Harvard Medical School, cell biologist Jeanne Lawrence at UMass Chan Medical School, and molecular biologist Jun Jiang has used a refined version of ...
Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren’t ...