MIT engineers develop a new system for precise control of synthetic gene expression, potentially advancing gene therapy.

Engineers have created DIAL, a modular system that precisely sets and edits protein levels in synthetic gene circuits. By ...

The expression of genes has to be carefully regulated in cells; active genes give cells their identity and ability to function. Epigenetic features are just one way that cells control gene expression, ...

The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

Molecular biologists have long believed that the beginning of a gene launched the process of transcription—the process by which a segment of DNA is copied into RNA and then RNA helps make the proteins ...

A figure from the paper illustates a key finding of "compromised compartmentalization": chromatin that was locking genes down in health became more open in Alzheimer's, while chromatin that was open ...

New work shows that physical folding of the genome to control genes located far away may have been an early evolutionary ...

Alida Biosciences’ EpiPlex platform uses robust assay controls and specialized bioinformatics to detect RNA modification, genomic coordinates, and relative quantity.

Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D ...

A study uncovers a cardiotoxic gene marker in cancer survivors linked to heart disease risk. Find out more about the results.