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Satisfactory renal function is a prerequisite of cisplatin-based chemotherapy and most clinical trials use calculated creatinine clearance (CrCl) of ≥60 ml/min as an eligibility criterion. CrCl has ...

A recent Lancet report has indicted that 10% of the world population suffers from some form of kidney disease.(1 ) . The simplest tool to measure and track kidney function is by GFR calculation using ...

Some health conditions, including those affecting the kidneys, can affect how much creatinine is excreted in your urine. Creatinine is a chemical waste product produced by muscle metabolism. When your ...

Creatinine is a breakdown product of muscle metabolism. The main route of creatinine excretion is through the kidneys, where it is filtered by the glomerulus and also secreted by the proximal tubule.

Creatine is a natural substance that helps supply energy to muscles. Creatinine is a waste product produced when creatine is broken down. Rhabdomyolysis, or "rhabdo," occurs when excessive creatinine ...

Two indices of creatinine clearance (an index of kidney function) are compared on a group of cancer patients who underwent chemotherapy with a potentially nephrotoxic drug. The standard index, ...