DNA damage can occur spontaneously or be caused by mutagenic chemicals and physical factors such as radiation and sunlight. These modifications must be corrected to avoid detrimental effects to the ...
Elaborate multiprotein assemblies serve myriad vital cellular roles throughout biology 1. Typically composed of a diverse suite of distinct types of catalytic folds and scaffolding elements, these ...
DNA sequencing by synthesis (SBS) offers an approach for potential high-throughput sequencing applications. In this method, the ability of an incoming nucleotide to act as a reversible terminator for ...
DNA damage repair starts with the recognition of damaged sites from predominantly normal DNA. In eukaryotes, diverse DNA lesions from environmental sources are recognized by the xeroderma pigmentosum ...
Why is DNA so important? Put simply, DNA contains the instructions necessary for life. The code within our DNA provides directions on how to make proteins that are vital for our growth, development, ...
Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules.
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