To evaluate its involvement in drug resistance in epilepsy and explore its pharmacogenomics, we typed the ABCB1 polymorphism (C to T) at position 3435 in 315 patients with epilepsy classified as ...

Review the definitions of drug solid form, polymorphism, crystallinity, and amorphicity. Understand the physical nature of polymorphism and the techniques used to find polymorphs, salts, and ...

Clinicians can test patients’ DNA for these enzyme polymorphisms. If a known polymorphism is detected, they can alter the dose or avoid certain drugs altogether if they don’t work as well as ...

Drug Ref. n Population Polymorphism(s) Results; Cyclosporine [10] 106: 100% Caucasian: CYP3A5 MDR1 (ABCB1) T-129C, C1236T, G2677(T,A), C3435T: No difference observed for cyclosporine and any ...

For most drug-metabolizing enzymes (DMEs), the functional consequences of genetic polymorphisms have been examined. Variants leading to reduced or increased enzymatic activity as compared to the ...

Individual differences in drug efficacy or toxicity can be influenced by genetic factors. We investigated whether polymorphisms of pharmacogenes that interfere with metabolism of drugs used in ...

Drug resistance is a major problem while treating chronic infections like HIV-1. ... Polymorphism: An Answer To Drug Resistance. by Bidita Debnath on October 8, 2012 at 10:06 PM. Facebook; ...

Did you know that certain medications can cause symptom of 'Genetic polymorphism'. Find these drugs listed on the page and be warned of similar symptoms as possible side-effects.

Drug polymorphism using FT-IR spectroscopic imaging: Purnima Parkhi Thursday, November 22, 2012, 08:00 Hrs [IST] The identification of polymorphs is best performed using Fourier Transform Infrared ...

Sodium diclofenac (see Figure 4) is a nonsteroidal anti-inflammatory drug that shows polymorphism. The sodium salt of the drug is manufactured by Novartis as "Voltaren." Frampton says there are three ...

For women with degenerative spondylolisthesis (DS), polymorphisms in the estrogen receptor α (ERα) are associated with back pain intensity.

The functional nonsynonymous single nucleotide polymorphism (rs6318) of the 5HTR2C gene is associated with increased risk of cardiovascular disease mortality and morbidity.