Electron tomography reveals the three-dimensional structure of membrane contact sites (colored red) between ER tubules (green) and mitochondria (purple) in a yeast cell (right) or an endosome ...

The mitochondria-endoplasmic reticulum contact sites (MERCS) also play a pivotal role in facilitating Ca 2+ transfer. Dysregulation at any level, such as excessive uptake or impaired efflux ...

Mitochondria are the powerhouses in our cells, producing the energy for all vital processes. Using cryo-electron tomography, ...

In addition to the nucleus, eukaryotic cells may contain several other types of organelles, which may include mitochondria, chloroplasts, the endoplasmic reticulum, the Golgi apparatus ...

The Ca2+ stored in the cellular endoplasmic reticulum (ER) plays a crucial role in protein folding and lipid transfer, and its impairment leads to cellular ER stress. When chronic cellular ER stress ...