Cellular identity is defined by gene activity that drives intercellular communication and is pivotal to understand mechanisms underlying multicellular organisms. In a new report Abbas Ghaddar and a ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 48 (November 27, 2018), pp. 12247-12252 (6 pages) According to the sensory drive model, variation in ...
Many antineoplastics are designed to target upregulated genes, but quantifying upregulation in a single patient sample requires an appropriate set of samples for comparison. In cancer, the most ...
Comparison of Fast-Progression, Hyperprogressive Disease, and Early Deaths in Advanced Non–Small-Cell Lung Cancer Treated With PD-1/PD-L1 Inhibitors or Chemotherapy PAM50-based subtype classification ...
The goal of gene therapy for patients with hemophilia A is to safely impart long-term stable factor VIII expression that predictably ameliorates bleeding with the use of the lowest possible vector ...