Recent progress in the molecular genetics of acute myeloid leukemia (AML) has shown this disease to be more heterogeneous than previously realized. Recurrent cytogenetic and mutational changes in ...

Using genetic fine-mapping analysis ... cells more chance to develop mutations that could eventually lead to overt leukemia." The new insights about IKZF1 bring researchers one step closer ...

The genetics behind the progression of myelodysplasia to secondary acute myeloid leukemia (sAML) is poorly understood. In this study, we profiled somatic mutations and their dynamics using next ...

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled “A case report of donor cell–derived ...

Scientists from Flinders University in Australia have made a surprising discovery about a recently identified type of genetic material called circular RNAs. Their research suggests that these ...

University of Illinois Chicago scientists have redesigned a treatment for the most common pediatric leukemia to eliminate its severe side effects, like blood clots and liver damage.

B-cell prolymphocytic leukemia (B-PLL) is a rare, aggressive type of leukemia that progresses rapidly. People with B-PLL typically have a less favorable outlook. However, new targeted treatments ...

University of Illinois Chicago scientists have redesigned a treatment for the most common pediatric leukemia to eliminate its severe side effects, like blood clots and liver damage. If approved ...

Chronic lymphocytic leukemia (CLL) tends to have a better outlook than most other types of leukemia. About 88% of adults over the age of 20 years live for 5 years post-diagnosis, and some can live ...