The Phase 2, randomized, double-blind clinical trial included 23 patients randomized to either 200 mg ataciguat (n=12) or placebo (n=11) once daily for a 12-month period. The primary Phase 2 clinical ...

An aortic stenosis murmur is an unusual sound the heart makes due to a narrowing of the aortic heart valve. The narrowed heart valve restricts blood flow from the heart, which can create a murmur.

More than 28 million people worldwide are living with heart valve disease, and the numbers are climbing. In the U.S., the ...

People living with aortic stenosis (AS) could gain earlier access to innovative care and treatment thanks to a new effort ...

A new study highlights the 'diagnostic pitfalls' behind missed aortic dissection, the condition that killed Canadian actor Alan Thicke ...

Surgery to replace an aortic valve is done for aortic valve stenosis and aortic valve regurgitation. During this surgery, the damaged valve is removed and replaced with an artificial valve. The valve ...

Aortic valve insufficiency is a form of valvular heart disease. It occurs when the aortic valve does not function properly. This may cause the heart to work harder and can lead to heart failure.

The companies have teamed to develop an alternative to TAVR that combines the benefits of a less-invasive procedure with the ...

Aortic stenosis is a narrowing of the aortic valve that affects how blood flows through the heart and body. While not often linked to heart valve narrowing, high and irregular blood pressure can ...

Aortic stenosis happens when your aortic valve does not open all the way causing pressure to build in the left ventricle. This pressure blocks blood flow as it leaves the heart. In other words, the ...