Sen and her colleagues studied fragments containing cryptic sites and compared the levels of histone methylation, which winds up DNA and switches it “off” by making it unavailable for transcription, ...

Interestingly, these "transcription-friendly" histone patterns were mutually ... That is, transcriptional activation was associated with methylation at K4, which paralleled acetylation of K9 ...

One function of histone modifications is to make DNA more or less accessible for transcription. Heterochromatin is highly ... they regulated that way,” remarked Cosgrove. “Generally, methylation at ...

These modifications, which include DNA methylation, histone modifications ... either by directly affecting transcription factors or by influencing their response to environmental changes.

DNA methylation, and histone modifications. Under Iestyn’s leadership, Richard Koche has been appointed as the Head of ERIL and leader of the computational unit and Pierre-Jacques Hamard has been ...