The GMoC system is therefore a more complete in vitro model because it replicates, architecturally, the cells lining the human intestine, and offers a more physiologically-relevant model compared ...

How will you create the mouse model? We will use germ-free mice — mice bred with no bacteria in their guts — to trial three methods of recreating the human small-intestinal microbiome in mice.

Researchers in the Liberali lab and their collaborators at the Institute of Science and Technology Austria created a model to explain how crypts form in intestinal organoids by linking mechanical ...

"Our aim was to create a system that more closely mimics human intestinal tissue. This model will allow us to study in detail key processes such as cell regeneration or changes associated with ...

Last October, another group of researchers published in Nature Medicine their success using pluripotent stem cells to grow miniature human intestines inside the kidneys of immunosuppressed mice. In ...

To measure such dysfunctions, the Ussing chamber is widely used, both for human and animal studies. This ex vivo approach to measure intestinal permeability requires intestinal tissue specimens ...

In the fight against bacterial pathogens, researchers are combining vaccination with targeted colonization of the intestine by harmless microorganisms. This approach could potentially mark a turning ...