The crystal structure of the hemagglutinin of both the viruses is similar, especially within the Sa antigenic site. Compared with seasonal influenza outbreaks, the overall impact of the 2009 H1N1 ...

Influenza vaccine efficacy studies entail ... which allow a more granular view of the hemagglutinin and neuraminidase genes, or even the entire genome.NGS can provide insight, including ...

and two subtypes of neuraminidase (N1 and N2) have caused sustained epidemics in the human population. Birds are hosts for all influenza A subtypes and are the reservoir from which new HA subtypes ...

Ongoing research projects include retinoids as chemopreventive and chemotherapeutic agents, inhibitors of influenza neuraminidase as orally active ... Crystallography (which has a strong program in ...

Baloxavir marboxil (baloxavir) rapidly reduces influenza virus shedding, which suggests that it may reduce transmission. Studies of treatment with neuraminidase inhibitors have not shown ...

While current influenza vaccines primarily target the variable hemagglutinin protein, the slower-evolving neuraminidase presents a promising target for the development of new vaccines providing ...