Macrophages use cell‑volume changes to sense danger, reprogram gene expression, and heighten inflammatory and antiviral responses.

As part of the body's first line of defense against foreign invaders, macrophages play an integral role in the innate immune ...

Researchers at Hannover Medical School (MHH) have developed a method for the efficient production of human immune cells, such ...

BIRMINGHAM, Ala. – Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages — the white blood cells that defend the body by killing microbes, ...

A new review published in Genes & Diseases highlights macrophage-targeted therapy as a promising frontier in cardiac regeneration and myocardial repair. The findings underscore the critical role of ...

When cancer cells begin to die within tumors, they expose signals on their surface that indicate they are dying. Macrophages then detect these signals and engage in phagocytosis, where they eat the ...

UCLA researchers have discovered that macrophages retain memories of previous immune threats due to the persistence of immune signaling molecules within tissues. Researchers from the University of ...

A new method combining AFM with deep learning accurately profiles human macrophage mechanophenotypes. Macrophages drive key immune processes including inflammation, tissue repair and tumorigenesis via ...

Macrophages are some of the body’s most potent weapons against invading cellular threats. Like immunological ‘Hungry Hungry Hippos,’ macrophages engulf and dispose of cancer cells or invasive ...

Aerobic glycolysis dominates lesion bioenergetics, with lactate promoting histone lactylation, M2 macrophage polarization, CD8⁺ T-cell exhaustion, EMT, and fibrosis that reinforce immune-protected ...