UC San Diego researchers have resolved a decades-long debate about the role of the first Crohn’s disease gene linked to an increased risk of developing the autoimmune condition. The human digestive ...

This granulomatous reaction may be viewed as a frustrated attempt by the immune system to neutralize antigen. The antigen is trapped within the granuloma and in this location the macrophages secrete ...

Aging immune cells known as senescent macrophages are emerging as critical players in cancer progression. Rather than defending the body, these aged cells undergo profound functional shifts that ...

Macrophages are critical immune cells that modulate the body’s response to infection, injury, inflammation, disease, and healing. Researchers differentiate and polarize cryopreserved monocytes into ...