Mitochondrial deoxyribonucleic acid (mtDNA) is essential for cellular energy production and overall cell function.

Researchers have now uncovered the role of mitochondrial transcription elongation factor in maintaining the balance between ...

Prince Frederik of Luxembourg died on March 1, 2025, at the age of 22 after a prolonged battle with POLG mitochondrial ...

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease ...

Prince Frederik, 22, was a founder and the creative director of a foundation that raised awareness of POLG disorder.

Accordingly, viral replication and success often depend on a virus's ability to evade or manipulate these essential regulatory mitochondrial processes. "From the point of view of the virus ...

et al. DNA precursor asymmetries in mammalian tissue mitochondria and possible contribution to mutagenesis through reduced replication fidelity. Proceedings of the National Academy of Sciences 102 ...

POLG is a genetic mitochondrial disorder that is very difficult to diagnose and treat. It causes progressive multiple organ ...

The replication system of archaea is largely ... All known eukaryotic cells contain mitochondria, or related organelles, which play central roles in energy conversion. These mitochondria retain ...