How cells 'back up' DNA replication to survive severe damage

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by ...

One missing metabolic step can turn cancer's DNA-copying machinery into a lethal weakness

Loss of an enzyme necessary for a process called lipoylation disrupts the way cancer cells copy their DNA, increasing their ...
Health And Pharma

Targeting RNase H2 Exposes a New Therapeutic Vulnerability in Triple-Negative Breast Cancer

Researchers at MD Anderson have identified RNase H2 as a key survival mechanism in triple-negative breast cancer, helping ...
ucdavis.edu

Computational Model Uses Language Theory to Predict DNA Shapes That Underlie Gene Expression and Disease

R-loops are structures that form when a strand of RNA (red) forms a stable structure with double-stranded DNA, causing one strand of the DNA to form a loop. R-loops are associated with gene ...