Gut microbiota produce trimethylamine, which enters the liver via the portal circulation and is primarily oxidized by FMO3 to produce TMAO. TMAO upregulates hepatic PCSK9 gene expression while ...
Calculous cholecystitis is a gallbladder inflammation that occurs due to the presence of gallstones (cholelithiasis). These gallstones can block the cystic duct, the channel through which bile flows ...