In 1987 I attended a meeting at Cold Spring Harbor on phosphatidylinositol signaling that turned out to be pivotal for me. A few years earlier I'd helped show that a phosphatidylinositol (PI) kinase ...

Control of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P 3) signals in cell survival, proliferation and growth is frequently dysfunctional in cancer, resulting in enhanced PtdIns(3,4,5 ...

The role of the adapter protein PICALM (phosphatidylinositol-binding clathrin ... rather than to defects in proximal insulin signaling. Consequently, elucidating the metabolic pathways associated ...