Few adverse effects have been reported from oral vitamin K. Conclusion: Phytonadione and menaquinone may be effective for the prevention and treatment of osteoporosis and arterial calcification.

increase in lumbar spine BMD significantly greater in group DK than group C 29 219 healthy men and women Phytonadione 1 mg/day for 2 wk In all treated groups, mean UcOC decreased from 7.6% to 3.4% ...