Future Microbiol. 2013;8(11):1431-1451. Bacterial contact with the platelets is a key event for the pathogenesis of sepsis, as deduced from the correlation between sepsis outcome and decreased ...

Innate immune system cells control megakaryopoiesis They discovered that the progenitor cells of MKs are fully consumed and constantly replaced during platelet formation (thrombopoiesis). This ...

Although cardiac stem cell therapy is a promising treatment for heart attack patients, directing the cells to the site of an injury – and getting them to stay there – remains challenging. In a new ...

Challenging a long-held model about how blood is formed, a study led by UC San Francisco researchers has found that the lungs play a crucial role in the process, producing half of blood platelets and ...

When a vascular injury occurs, platelets in young mice form much smaller blood clots (left) than platelets in old mice (right), where the clot almost blocks the blood vessel. Fluorescence microscopy ...

Cancer researchers report that blood platelets blunt the immune response to cancer. Genetic inactivation of platelets improved the ability of T cells to fight melanoma in preclinical tests. Adoptive T ...

A cut presumably draws blood anywhere in the universe, whether in an Earthly suburb or on some future interstellar voyage yet undreamed outside science fiction. In space, however, clotting's the ...

Platelets are small, disk-shaped cell fragments in the blood that are essential to stop bleeding and to initiate blood clotting after injury. Platelet transfusions in patients with severe trauma or ...

Platelets have been shown to cover a broad range of functions. Besides their role in hemostasis, they have immunological functions and thus participate in the interaction between pathogens and host ...