Rapid and extensive Schwann cell death under high-glucose pyruvate-depleted conditions can be evoked by the following sequential metabolic alterations; 1) diminished TCA cycle intermediates and ...

Using a gas chromatography–mass spectrometry (GC–MS) method with stable isotope internal standards, 3 we measured concentrations of sorbitol and its polyol pathway metabolite, fructose, as well as ...

Human epithelial ovarian tumours represent a major type of gynaecologic malignancy. The vast majority of ovarian carcinomas arise as a result of malignant transformation of the ovarian surface ...