Recent advances in synthetic polypeptide and polymer chemistry have transformed the landscape of biomaterials by combining the precision of organic synthesis with the versatile functionalities of ...

Advances in N-carboxyanhydride (NCA) ring-opening polymerization are making polypeptide synthesis faster, more moisture-resistant, and easier to scale. New initiators, solvent systems, and process ...

Animals such as spiders make fibers which are strong and elastic. These fibers have a polypeptide structure and serve as inspiration for research into the development of functional materials.

Aza-peptides, peptide analogues in which one or more α-carbon atoms are replaced by nitrogen atoms, represent a promising class of compounds in therapeutic development. This structural modification ...

A major problem in solid-phase peptide synthesis (SPPS) is aggregation and poor solvation leading to incomplete deprotection and/or coupling steps, resulting in low crude purity peptides. 1 This ...

Ozempic has been making headlines for its remarkable success in treating obesity and diabetes. Yet it is just one in a rapidly growing class of drugs called peptide therapeutics that sits between ...

In nature, there are animals that make fibers that are strong and elastic—for example, the thread that spiders produce to make webs. These fibers have a polypeptide structure and serve as inspiration ...

Fibrous structures act as load-bearing components in vivo in many natural proteins besides enzymes, which are soluble globular molecules. Natural evolutionary processes have produced structural ...

From anti-aging skin care to weight-loss treatments, peptides have quickly moved into the spotlight. Two Georgia doctors ...