Owing to its highly polymorphic nature and major contribution to the metabolism and bioactivation of numerous clinically used drugs, CYP2D6 is one of the most extensively studied drug-metabolizing ...

Population genetics is the study of the genetic composition of populations, including distributions and changes in genotype and phenotype frequency in response to the processes of natural ...

Guidance from the American Academy of Pediatrics covers multiple genetic testing approaches to diagnosing developmental delay ...

Because most human genetic variation is within rather than between populations, 10,40 only a fraction of gene variants will both display large differences in allele frequency between the populations ...

In a clinical report issued by the American Academy of Pediatrics and published online June 23 in Pediatrics, guidance is ...

Cohn, ES, Kelley, PM. Clinical phenotype and mutations in connexin 26 (DFNB1/GJB2), the most common cause of childhood hearing loss. ... MM. Population-based genetic screening for reproductive ...

This study provides the first extensive genetic and phenotype landscape of PPCM and has major implications for understanding how PPCM ... compared with just 1.2 percent of the reference population.

Blood samples and associated phenotype data such as weight, height, hip circumference, waist circumference and blood pressure were collected from 20,000 individuals representing 83 population ...

TOPLINE: A commercially available test for 40 genetic variants that identifies people with the "hungry gut" obesity phenotype can predict who will respond most to semaglutide for weight management ...

It's not another tall tale: Evolutionary biologists have developed a new understanding of the genetic basis of short stature in humans. Also known as the pygmy phenotype, a study published Monday ...

Guidance is provided for the pediatrician regarding the genetic evaluation of developmental delay/intellectual disability.