A new method that successfully designs serine hydrolase enzymes capable of catalyzing ester hydrolysis with high efficiency, demonstrates a computational approach for creating de novo enzymes that ...

Researchers have captured real-time "molecular movies" showing how an enzyme changes shape during catalysis. The study was published in Nature Communications.

Enzymes that originally evolved in high-temperature environments later adapted to cooler conditions as Earth underwent global cooling. Now, researchers from Waseda University and RIKEN in Japan have ...