Three major pathways involved in abnormal proliferation and contraction of the smooth-muscle cells of the pulmonary artery in patients with pulmonary arterial hypertension are shown. These pathways ...
The Fontan operation and its variants have become the procedures of choice in patients with one anatomical or functional ventricular chamber. In a normal biventricular heart, the systemic and ...
This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major ...
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