Cancer metastasis is a crucial area in cancer research that directly affects patient survival and treatment outcomes. Cancer cells often undergo adaptive metabolic changes during metastasis from in ...

image: Medical College of Georgia researchers are trying to open a door for a killer that breast cancer cells shut out. Pyruvate is a metabolite in the blood that is lethal to rapidly-multiplying ...

Failure to import pyruvate into the mitochondria of cardiomyocytes results in metabolic maladaptation, cardiac hypertrophy and heart failure, thus underscoring the central role of pyruvate metabolism ...

Investigators at KU Leuven have discovered that although mTOR signaling was important in primary breast tumors and lung metastases alike, the signals that activated mTOR were different between the two ...

Pyruvate is produced by glycolysis, a process in which carbohydrates are broken down to create energy. Calcium pyruvate is a popular supplement that many people use primarily for its purported weight ...