Figure 1. (Left) Pre- and (Right) Post-fusion forms of the RSV F protein. Protein structural arrangement occurs during the host-virus membrane fusion, signaling viral infection. 5 Image Credit ...

Scientists have long attempted to create vaccines that coax the immune system into recognizing the fusion (F) proteins ...

Scientists have long attempted to create vaccines that coax the immune system into recognizing the fusion (F) proteins present on the surfaces of RSV, hMPV and related viruses.

It targets the RSV fusion protein and the target site in the epitope that is present. There are two confirmations of this protein: the pre- and the post-fusion confirmation.

"Here, we assessed the effect of RSV fusion protein conformation on B cell responses," Chang added, referring to her team's findings, which are published in the journal Science Translational Medicine.

The oral respiratory syncytial virus (RSV) fusion protein inhibitor AK0529 was found to be well tolerated and reduced viral load in infants. Both viral load and Wang Respiratory Scores improved ...

It is a recombinant neutralizing humanized immunoglobulin G1 kappa monoclonal antibody directed against the prefusion conformation of the RSV fusion (F) protein. Essentially, it binds to the F ...

In most people, the lung-infecting pathogens known as respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) trigger mild cold-like symptoms. But in infants and seniors, these viruses can ...

RSV is of the greatest concern for young children, the elderly and adults at high risk for respiratory complications. Yet unlike the flu and other common, communicable respiratory illnesses that ...