Renal drug excretion involves filtration, reabsorption, and secretion, crucial for drug clearance and minimizing toxicity. The study models renal clearance using pharmacokinetic parameters, validated ...

Augmented renal clearance (ARC) refers to an enhanced kidney filtration process, typically defined as a creatinine clearance exceeding 130 mL/min/1.73 m². This phenomenon is increasingly recognised in ...

Please provide your email address to receive an email when new articles are posted on . The “strong associations” of urine-to-plasma ratios with cardiovascular mortality implies a connection between ...

A U of A researcher is leading a study that could help save the lives of people in intensive care whose kidneys work too well, flushing out critical medications before they can do their job.

Upon intravenous administration, NPs and NMs enter the vascular system and are distributed to the organs and peripheral tissues of the body. Within the vascular compartment these particles or ...

Science Progress (1933-) Vol. 104, No. 2, 2021 Augmented renal clearance. An unnoticed relevant event This is the metadata section. Skip to content viewer section. Augmented renal clearance (ARC) is a ...

In the United States, the annual rate of growth in incident patients with end-stage kidney disease has slowed. However, patients selecting home dialysis for the first time increased 85.6% from 2007 to ...

There is renewed interest in employing sorbent technologies, such as activated carbon, to aid removal of uremic solutes, especially in home and portable dialysis. Activated carbon may allow additional ...

Sepsis continues to be a leading cause of mortality in ICUs worldwide. Despite advances in early detection and treatment, ...