Endogenous retroviruses are remnants of ancient viral infections that have integrated into the germline DNA of their hosts, becoming a permanent part of the host genome. These viral sequences ...

On the other hand, Gag selects the genomic RNA among the multitude of cellular or viral RNA species in the cytoplasm of infected cells, to ensure its encapsidation. To achieve this, Gag binds to a ...

To conceptualize this transformation, let's examine the replication of retroviruses, the family of viruses to which HIV belongs. This process very closely mirrors the movement of an important ...

Retroviruses are a sub-category of oncoviruses that include the lentiviruses. Retroviruses are negative single-stranded RNA viruses in which tRNA serves as a primer for the mRNA synthesis. The mRNA is ...

Studies the envelope proteins of viruses, including retroviruses and the Ebola virus. These proteins are responsible for binding and fusing the virus to target cell membranes. Also looking at ways to ...

Remnants of ancient viral pandemics in the form of viral DNA sequences embedded in our genomes are still active in healthy people, according to new research my colleagues and I recently published.

It would be another two years before French researchers would identify a retrovirus as the cause of AIDS, or acquired ...

After integration, the 5'-LTR controls viral transcription, which is performed by the cellular transcription machinery. The complex retroviruses, such as HIV, encode additional trans-regulating ...

Current research suggests that viral hitchhikers in human DNA may play roles in cancer, inflammation, and neurodegenerative disorders. The mechanisms that underpin these connections between human ...

How did viruses evolve? Are they a streamlined form of something that existed long ago, or an ultimate culmination of smaller genetic elements joined together?

Over millennia, our cells and the cells of other primates that are susceptible to retrovirus infection have evolved strategies to rebuff the viruses. In turn, retroviruses like HIV have evolved their ...

It would be another two years before French researchers would identify a retrovirus as the cause of ... It would be another three years before that virus would get its name HIV, or human ...