They tracked purine production across six mouse cancer models, including xenograft breast and colon tumors. They infused the mice with tagged nutrients that fed either the de novo or the salvage ...

This enzyme is involved in purine salvage, and its deficiency leads to the accumulation of uric acid and neurological symptoms. Purine metabolism and signaling pathways are potential targets for ...

Nature Research Intelligence Topics enable transformational understanding and discovery in research by categorising any document into meaningful, accessible topics. Read this blog to understand ...