The model focuses on orthopoxviruses—which includes the viruses that cause smallpox and mpox ... "If you are looking for the reservoir for mpox virus in Central Africa, that's one of the ...

The recent global monkeypox (mpox) outbreak, with a new and aggressive variant, has underscored the dire need for safe, broadly effective, and accessible vaccines. The LC16m8 vaccine, an attenuated ...

Researchers have employed a cross-species immunological analysis to provide new insights into a smallpox vaccine's ...

In recent years, the world has seen a surge in new and deadly infectious diseases, posing a major threat to global health.

Attempts to develop a nonhuman primate model of variola infection ... Prophylactic immunization using vaccinia virus facilitated the eradication of smallpox. Concerns on the possible use of ...

Samples of smallpox virus are not needed for the production or further development of new vaccines or drugs because animal model poxviruses are used instead. If smallpox were to be genetically ...

Sanofi Pasteur smallpox vaccine (SPSV ... highly attenuated vaccinia virus MVA: derived from more than 570 serial passages in chicken embryo fibroblasts: IMVAMUNE (Bavarian-Nordic); TBC-MVA ...

Not so with smallpox. To create this vaccine, you begin with another virus that is similar to the smallpox virus, yet different enough not to bring on the smallpox disease once it enters your body.

Smallpox, or variola, virus has killed more human beings than any other infectious agent. Fortunately, smallpox virus has only one host-humans -- which made it possible to eradicate it. In 1967, the ...

parents didn't name their children until they had survived a bout with the virus. Smallpox was the single deadliest disease during the 18th century, striking commoners and royalty alike.

Smallpox, one of the biggest killers in history, is caused by a virus called variola. Variola causes a distinctive rash and is often lethal. The name variola comes from the Latin word for “spotted” ...

they tested the sample for virus DNA—and instead found the variola virus, which causes smallpox. Known for its signature blisters and gruesome deaths, smallpox killed 300 million people in the ...