The model focuses on orthopoxviruses—which includes the viruses that cause smallpox and mpox ... "If you are looking for the reservoir for mpox virus in Central Africa, that's one of the ...

The recent global monkeypox (mpox) outbreak, with a new and aggressive variant, has underscored the dire need for safe, broadly effective, and accessible vaccines. The LC16m8 vaccine, an attenuated ...

Researchers have employed a cross-species immunological analysis to provide new insights into a smallpox vaccine's ...

In recent years, the world has seen a surge in new and deadly infectious diseases, posing a major threat to global health.

Attempts to develop a nonhuman primate model of variola infection ... Prophylactic immunization using vaccinia virus facilitated the eradication of smallpox. Concerns on the possible use of ...

Samples of smallpox virus are not needed for the production or further development of new vaccines or drugs because animal model poxviruses are used instead. If smallpox were to be genetically ...

Not so with smallpox. To create this vaccine, you begin with another virus that is similar to the smallpox virus, yet different enough not to bring on the smallpox disease once it enters your body.

current international concern exists regarding the potential use of smallpox virus as an agent for bioterrorism. This manuscript reviews clinical aspects of smallpox, smallpox immunization ...

Smallpox, one of the biggest killers in history, is caused by a virus called variola. Variola causes a distinctive rash and is often lethal. The name variola comes from the Latin word for “spotted” ...

they tested the sample for virus DNA—and instead found the variola virus, which causes smallpox. Known for its signature blisters and gruesome deaths, smallpox killed 300 million people in the ...