Few elderly patients have been included in randomized trials assessing recombinant tissue plasminogen activator (rtPA) in stroke. In North America, intravenous thrombolysis is allowed in these ...

An individual patient-level meta-analysis shows that tenecteplase, a next-generation thrombolytic, is at least as effective as alteplase for acute stroke — and may be superior.

Making the switch from alteplase to tenecteplase for stroke thrombolysis can be done successfully when the appropriate preparations are taken, and it may improve patient outcomes, the experience of a ...

Comprehensive protocols in emergency departments (EDs) can allow rapid assessment of stroke patients eligible for early-stage treatment, according to a study published in the latest Medical Journal of ...

Among Chinese patients with minor nondisabling stroke who presented within 4.5 hours of symptom onset, dual antiplatelet treatment was noninferior to thrombolysis with intravenous alteplase with ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Thrombolytic Science, LLC (TSI) today announced initiation of a Phase 2 clinical trial to confirm the efficacy and safety of its sequential dual-treatment regimen of ...

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Restrictions to thrombolytic therapy for stroke—recommended only up to 4.5 h after onset and in those under 80 years of age—limit its use. Results from a recent trial support expansion of both the ...

Argentina: A recent systematic review and meta-analysis published in the Journal of Thrombosis and Thrombolysis compared ...

Background: Thrombolysis for acute ischemic stroke has remained controversial. The Canadian Alteplase for Stroke Effectiveness Study, a national prospective cohort study, was conducted to assess the ...

PHOENIX -- Sooner is better for intravenous thrombolysis (IVT) given before mechanical thrombectomy for acute ischemic stroke, a meta-analysis of patient-level data from randomized controlled trials ...

Carotid artery stenting (CAS) or carotid endarterectomy (CEA) performed early after thrombolysis for acute stroke appears safe, with no increased risk of serious complications, according to a Swedish ...