Cytokines are secreted proteins critical for immune regulation, cell signaling, and tissue homeostasis. These cells are increasingly recognized as key tools in biomedical research, particularly in ...

Sanofi’s success co-developing a blockbuster drug based on blocking the signaling of interleukin 4 and interleukin 13 (IL-4 and IL-13) makes it an ideal partner to collaborate on inflammatory ...

Structural equivalence is demonstrated through the comparison of a synthetic multinuclear metal complex (left) versus the designer enzyme in this report (right). A collaborative research team led by ...

Psoriasis, a chronic inflammatory skin condition characterized by dry and scaly skin lesions, affects about 7.5 million people in the United States. Psoriasis results from abnormal proliferation of ...

Microglial cells, the primary immune cells of the brain and central nervous system, are known to undergo striking morphological changes in response to sensory or neural stimuli. However, the ...

A collaborative research team has successfully developed designer enzymes that exhibit both intrinsic and extrinsic functions by transplanting a synthetic trinuclear zinc center into a human cytokine.