Researchers have identified a small-molecule compound that appears to counteract weight gain and metabolic damage in mice ...

In a struggle that probably sounds familiar to dieters everywhere, the less a Caenorhabditis elegans (C. elegans) worm eats, the more slowly it loses fat. Now, scientists have discovered why: a small ...

Scientists have identified a compound that promotes weight loss without the bone damage seen in restrictive diets.

In a struggle that probably sounds familiar to dieters everywhere, the less a Caenorhabditis elegans (C. elegans) worm eats, the more slowly it loses fat. Now, scientists at Scripps Research have ...

BUFFALO, N.Y. — When cells experience enough chronic stress, they can stop dividing permanently. In this state of cellular limbo, known as replicative senescence, cells remain alive but no longer ...

When starved of oxygen during a heart attack or stroke, cells unleash a flurry of emergency measures to protect themselves and the body. For decades, scientists have observed that the body's ...

Most fat stores energy; the body's brown fat does the opposite. Unlike the white fat that accumulates just under our skin, ...

Scripps Research scientists discovered that specialized intestine cells (shown in green) in the C. elegans worm (gray) produce a peptide hormone that travels to the brain to control fat metabolism.