The assembly of a bipolar microtubule-based spindle is crucial for the accurate and timely segregation of the chromosomes into the two daughter cells during mitosis. Three microtubule nucleation ...

In the cell, microtubule organizing centers (MTOCs) dynamically nucleate microtubules and arrange them in functional patterns, but microtubule anchoring to MTOCs is not well understood. A novel ...

During cell division, adherent animal cells round up to create the precise spatial geometry required for accurate chromosome segregation, a process that depends on the coordinated remodeling of the ...

Cell division ensures growth or renewal and is thus vital for all organisms. However, the process differs somewhat in animals, bacteria, fungi, plants, and algae. Until now, little was known about how ...