To further analyze antigen processing, Ralph Wieneke, Robert Tampé, and their team at the University of Frankfurt am Main (Germany) have now developed a photostimulated antigen release system ...

Processing of some antigens by standard proteasome but not by the immunoproteasome result in poor presentation by dendritic cells. Immunity 12 , 101?117 ( 2000). Article Google Scholar ...

Antigen processing of HIV-1 proteins has received little attention; the most intense focus has been on the effect of mutations on epitope recognition by CTLs.

Antigen processing and presentation, as a central link connecting innate and adaptive immunity, are precisely regulated by ROS. Physiological concentrations of ROS can promote adaptive immune ...

Immune system in the spotlight Light-controlled antigen release for analysis of antigen processing Date: July 16, 2024 Source: Wiley Summary: Our immune system is always on alert, detecting and ...

A cell-free antigen processing system informs HIV-1 epitope selection and vaccine design. Journal of Experimental Medicine , 2023; 220 (7) DOI: 10.1084/jem.20221654 Cite This Page : ...

Our simple method, called reductionist cell-free antigen processing, reproduces in a test tube the complex events that occur in the human immune system as a response to antigens, foreign invaders ...

Limited data exist on the potential role of alterations in HLA Class I antigen processing and presentation machinery (APM) in mediating response to ICB. Methods: We conducted a retrospective cohort ...

The WT1 protein expression was detected by western blotting with a commercially available WT1 monoclonal antibody. Intracellular flow cytometry with monoclonal antibodies was used to study the ...

More information: Mariana P. Cervantes-Silva et al, The circadian clock influences T cell responses to vaccination by regulating dendritic cell antigen processing, Nature Communications (2022 ...

The assay identifies antigens that are displayed to T cells by Class II HLA molecules on dendritic cells, which is the most direct way for measuring antigen processing and presentation. ProPresent is ...

Weekly rapid antigen testing can be deployed in meat-processing plants to limit the spread of Covid-19, the State’s health watchdog has recommended.