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While mRNA vaccines represent a transformative platform for infectious disease control, their efficacy in antigen-presenting cells (APCs) remains vulnerable to endogenous regulatory networks, ...
Discover a study where researchers have discovered a myeloid-derived antigen-presenting cells population essential for peripherally induced regulatory T cells.
As an alternative to the conventional approach of accessing native APCs and using them to ... Acellular artificial antigen-presenting cells (aAPCs) are micro- or nano-particle-based reductionist ...
Panelists discuss how chronic graft-vs-host disease (cGVHD) results from complex biological mechanisms involving inflammation, loss of peripheral tolerance, and fibrotic pathways affecting multiple ...
Once inside the lymph node, the amphiphile lets go of albumin, allowing the drug to be taken up by antigen-presenting cells (APC), which stimulate a tumor-targeting T-cell response. The company ...
cytoplasmic entry into antigen-presenting cells (APCs), APC activation and endoplasmic reticulum targeting,” said Wang Ji, a researcher with the Institute of Precision Medicine at the First ...
Replimune Group, Inc.'s RP1 + OPDIVO for advanced melanoma gains FDA Priority Review. PDUFA date: July 22, 2025. Read more on ...
The intestinal immune system is complicated machinery. Tolerance to food begins with antigen presenting cells, or APCs, instructing T cells to stand down. This signal gives rise to pTregs, a special ...
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