Skeletal muscle is made up of bundles of contracting muscle fibers and each muscle fiber is surrounded by satellite cells--muscle stem cells that can produce new muscle fibers.

Sustained Activation of mTORC1 in Skeletal Muscle Inhibits Constitutive and Starvation-Induced Autophagy and Causes a Severe, Late-Onset Myopathy. Cell Metabolism , 2013; DOI: 10.1016/j.cmet.2013. ...

Researchers building a model of muscle damage in a cultured system found that components leaking from broken muscle fibers activate ''satellite cells,'' which are muscle stem cells. While ...

A TBP-containing TFIID-protein complex activates genes that regenerate muscle tissue, ... Defining the Components Needed to Regenerate Skeletal Muscle. by Bidita Debnath on February 11, 2016 at 2: ...

The generation of functional skeletal muscle tissues from human pluripotent stem cells (hPSCs) has not been reported. Here, we derive induced myogenic progenitor cells (iMPCs) via transient ...

These 'mini-muscles' of non-muscle cells, called stress fibers, are composed of the same central players (actin and myosin) as the contractile units of muscles. Within our bodies, skeletal muscles ...

Research groups at the University of Helsinki uncovered how motor protein myosin, which is responsible for contraction of skeletal muscles, functions also in non-muscle cells to build contractile ...